Empowering families. Accelerating genetic breakthroughs.
Cri du Chat Research Foundation transforms personal heartbreak into hope-driving innovative science to improve lives and independence for everyone affected by 5p- syndrome.
Founded by families, powered by volunteers, we advance research and foster hope for those living with 5p- syndrome. Every dollar goes directly to science, accelerating breakthroughs that can change lives.
Our Legacy, Their Future
After receiving her son’s diagnosis, Megan Leston and her family turned heartbreak into action-founding CDCRF to drive research, spark hope, and change the future for everyone affected by 5p- syndrome. Watch Megan share why this mission matters and how you can be part of it.
What is Cru du Chat Syndrome?
Every year, 50 to 60 U.S. families welcome a child with 5p- syndrome-a rare genetic condition that challenges, but never defines, their potential.
Raise the Volume for 5p- Syndrome
Join us on Saturday, January 31, 2026 for an unforgettably fun evening. Enjoy a feel-good night of delicious food, Music, themed gift baskets & raffles, Inspiration and community. We’re coming together to honor children and adults living with 5p- Syndrome, raise awareness for this rare disease and raise $150,000 to screen 5,000 potential drugs — including gene therapies — using brain cells from individuals with 5p- Syndrome.
Your gift fuels breakthrough research.
Every donation supports families facing 5p- syndrome and drives progress toward new treatments. As a volunteer-run, tax-exempt nonprofit, every dollar goes directly to science and hope.
“Have courage—embrace hope and trust in the promise of the future. Now is the time for us to dream boldly.” - Co-Founder, Megan Leston
Stay connected with CDCRF.
Be the first to hear about upcoming events, research updates, and ways to make a difference for families affected by 5p- syndrome.